SrasV1, Main, Exploration, bibRecord, 006055

Cloaked similarity between HIV-1 and SARS-CoV suggests an anti-SARS strategy.

Identifieur interne : 006055 ( Main/Exploration ); précédent : 006054; suivant : 006056

Cloaked similarity between HIV-1 and SARS-CoV suggests an anti-SARS strategy.

Auteurs : Yossef Kliger [Israël] ; Erez Y. Levanon

Source :

BMC microbiology [ 1471-2180 ] ; 2003.

RBID : pubmed:14499001

Descripteurs français

KwdFr :
- Agents antiVIH (pharmacologie), Antiviraux (pharmacologie), Conception de médicament, Conformation des protéines, Données de séquences moléculaires, Fragments peptidiques (pharmacologie), Protéine d'enveloppe gp41 du VIH (pharmacologie), Protéines de fusion virale (), Protéines de fusion virale (génétique), Protéines de fusion virale (métabolisme), VIH-1 (Virus de l'Immunodéficience Humaine de type 1) (), Virus du SRAS ().
MESH :
- génétique : Protéines de fusion virale.
- métabolisme : Protéines de fusion virale.
- pharmacologie : Agents antiVIH, Antiviraux, Fragments peptidiques, Protéine d'enveloppe gp41 du VIH.
- Conception de médicament, Conformation des protéines, Données de séquences moléculaires, Protéines de fusion virale, VIH-1 (Virus de l'Immunodéficience Humaine de type 1), Virus du SRAS.

English descriptors

KwdEn :
- Anti-HIV Agents (pharmacology), Antiviral Agents (pharmacology), Drug Design, Enfuvirtide, HIV Envelope Protein gp41 (pharmacology), HIV-1 (chemistry), HIV-1 (drug effects), Molecular Sequence Data, Peptide Fragments (pharmacology), Protein Conformation, SARS Virus (chemistry), SARS Virus (drug effects), Viral Fusion Proteins (chemistry), Viral Fusion Proteins (genetics), Viral Fusion Proteins (metabolism).
MESH :
- chemical , chemistry : Viral Fusion Proteins.
- chemical , genetics : Viral Fusion Proteins.
- chemical , metabolism : Viral Fusion Proteins.
- chemical , pharmacology : Anti-HIV Agents, Antiviral Agents, HIV Envelope Protein gp41, Peptide Fragments.
- chemistry : HIV-1, SARS Virus.
- drug effects : HIV-1, SARS Virus.
- Drug Design, Enfuvirtide, Molecular Sequence Data, Protein Conformation.

Abstract

Severe acute respiratory syndrome (SARS) is a febrile respiratory illness. The disease has been etiologically linked to a novel coronavirus that has been named the SARS-associated coronavirus (SARS-CoV), whose genome was recently sequenced. Since it is a member of the Coronaviridae, its spike protein (S2) is believed to play a central role in viral entry by facilitating fusion between the viral and host cell membranes. The protein responsible for viral-induced membrane fusion of HIV-1 (gp41) differs in length, and has no sequence homology with S2.

DOI: 10.1186/1471-2180-3-20
PubMed: 14499001

Affiliations:

Israël

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Cloaked similarity between HIV-1 and SARS-CoV suggests an anti-SARS strategy.</title>
<author><name sortKey="Kliger, Yossef" sort="Kliger, Yossef" uniqKey="Kliger Y" first="Yossef" last="Kliger">Yossef Kliger</name>
<affiliation wicri:level="1"><nlm:affiliation>Compugen LTD, Tel Aviv, 69512, Israel. kliger@compugen.co.il</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Compugen LTD, Tel Aviv, 69512</wicri:regionArea>
<wicri:noRegion>69512</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Levanon, Erez Y" sort="Levanon, Erez Y" uniqKey="Levanon E" first="Erez Y" last="Levanon">Erez Y. Levanon</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2003">2003</date>
<idno type="RBID">pubmed:14499001</idno>
<idno type="pmid">14499001</idno>
<idno type="doi">10.1186/1471-2180-3-20</idno>
<idno type="wicri:Area/PubMed/Corpus">003182</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">003182</idno>
<idno type="wicri:Area/PubMed/Curation">003182</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">003182</idno>
<idno type="wicri:Area/PubMed/Checkpoint">003299</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">003299</idno>
<idno type="wicri:Area/Ncbi/Merge">000344</idno>
<idno type="wicri:Area/Ncbi/Curation">000344</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000344</idno>
<idno type="wicri:Area/Main/Merge">006555</idno>
<idno type="wicri:Area/Main/Curation">006055</idno>
<idno type="wicri:Area/Main/Exploration">006055</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Cloaked similarity between HIV-1 and SARS-CoV suggests an anti-SARS strategy.</title>
<author><name sortKey="Kliger, Yossef" sort="Kliger, Yossef" uniqKey="Kliger Y" first="Yossef" last="Kliger">Yossef Kliger</name>
<affiliation wicri:level="1"><nlm:affiliation>Compugen LTD, Tel Aviv, 69512, Israel. kliger@compugen.co.il</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Compugen LTD, Tel Aviv, 69512</wicri:regionArea>
<wicri:noRegion>69512</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Levanon, Erez Y" sort="Levanon, Erez Y" uniqKey="Levanon E" first="Erez Y" last="Levanon">Erez Y. Levanon</name>
</author>
</analytic>
<series><title level="j">BMC microbiology</title>
<idno type="eISSN">1471-2180</idno>
<imprint><date when="2003" type="published">2003</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Anti-HIV Agents (pharmacology)</term>
<term>Antiviral Agents (pharmacology)</term>
<term>Drug Design</term>
<term>Enfuvirtide</term>
<term>HIV Envelope Protein gp41 (pharmacology)</term>
<term>HIV-1 (chemistry)</term>
<term>HIV-1 (drug effects)</term>
<term>Molecular Sequence Data</term>
<term>Peptide Fragments (pharmacology)</term>
<term>Protein Conformation</term>
<term>SARS Virus (chemistry)</term>
<term>SARS Virus (drug effects)</term>
<term>Viral Fusion Proteins (chemistry)</term>
<term>Viral Fusion Proteins (genetics)</term>
<term>Viral Fusion Proteins (metabolism)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Agents antiVIH (pharmacologie)</term>
<term>Antiviraux (pharmacologie)</term>
<term>Conception de médicament</term>
<term>Conformation des protéines</term>
<term>Données de séquences moléculaires</term>
<term>Fragments peptidiques (pharmacologie)</term>
<term>Protéine d'enveloppe gp41 du VIH (pharmacologie)</term>
<term>Protéines de fusion virale ()</term>
<term>Protéines de fusion virale (génétique)</term>
<term>Protéines de fusion virale (métabolisme)</term>
<term>VIH-1 (Virus de l'Immunodéficience Humaine de type 1) ()</term>
<term>Virus du SRAS ()</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Viral Fusion Proteins</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Viral Fusion Proteins</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Viral Fusion Proteins</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Anti-HIV Agents</term>
<term>Antiviral Agents</term>
<term>HIV Envelope Protein gp41</term>
<term>Peptide Fragments</term>
</keywords>
<keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>HIV-1</term>
<term>SARS Virus</term>
</keywords>
<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>HIV-1</term>
<term>SARS Virus</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Protéines de fusion virale</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Protéines de fusion virale</term>
</keywords>
<keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Agents antiVIH</term>
<term>Antiviraux</term>
<term>Fragments peptidiques</term>
<term>Protéine d'enveloppe gp41 du VIH</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Drug Design</term>
<term>Enfuvirtide</term>
<term>Molecular Sequence Data</term>
<term>Protein Conformation</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Conception de médicament</term>
<term>Conformation des protéines</term>
<term>Données de séquences moléculaires</term>
<term>Protéines de fusion virale</term>
<term>VIH-1 (Virus de l'Immunodéficience Humaine de type 1)</term>
<term>Virus du SRAS</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Severe acute respiratory syndrome (SARS) is a febrile respiratory illness. The disease has been etiologically linked to a novel coronavirus that has been named the SARS-associated coronavirus (SARS-CoV), whose genome was recently sequenced. Since it is a member of the Coronaviridae, its spike protein (S2) is believed to play a central role in viral entry by facilitating fusion between the viral and host cell membranes. The protein responsible for viral-induced membrane fusion of HIV-1 (gp41) differs in length, and has no sequence homology with S2.</div>
</front>
</TEI>
<affiliations><list><country><li>Israël</li>
</country>
</list>
<tree><noCountry><name sortKey="Levanon, Erez Y" sort="Levanon, Erez Y" uniqKey="Levanon E" first="Erez Y" last="Levanon">Erez Y. Levanon</name>
</noCountry>
<country name="Israël"><noRegion><name sortKey="Kliger, Yossef" sort="Kliger, Yossef" uniqKey="Kliger Y" first="Yossef" last="Kliger">Yossef Kliger</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 006055 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 006055 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    SrasV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:14499001
   |texte=   Cloaked similarity between HIV-1 and SARS-CoV suggests an anti-SARS strategy.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:14499001" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a SrasV1

This area was generated with Dilib version V0.6.33.
Data generation: Tue Apr 28 14:49:16 2020. Site generation: Sat Mar 27 22:06:49 2021

Serveur d'exploration SRAS

Cloaked similarity between HIV-1 and SARS-CoV suggests an anti-SARS strategy.

Cloaked similarity between HIV-1 and SARS-CoV suggests an anti-SARS strategy.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration SRAS
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.